https://www.biorxiv.org/content/10.1101/2024.10.29.620830v1 A pre print describing how NINJ1 prevents HSV-1 from entering mouse macrophages
Author: Ella Hartenian
Graduate Student at University of California Berkeley
A review on NINJ1 and mechanisms of plasma membrane rupture
Saray and Ella collaborate to write a review on mechanisms of plasma membrane rupture https://pubmed.ncbi.nlm.nih.gov/38906725/
Structural basis of NINJ1-mediated plasma membrane rupture in cell death
Our new paper from the Broz lab! https://www.nature.com/articles/s41586-023-05991-z
Xrn1 activity broadly represses RNA polymerase II occupancy at mammalian but not viral promoters during herpesvirus infection
Abstract In mammalian cells, widespread acceleration of cytoplasmic mRNA degradation is linked to impaired RNA polymerase II (Pol II) transcription. This mRNA decay-induced transcriptional repression occurs during infection with gammaherpesviruses including Kaposi’s sarcoma-associated herpesvirus (KSHV) and murine gammaherpesvirus 68 (MHV68), which encode an mRNA endonuclease that initiates widespread RNA decay. Here, we show that MHV68-induced…
Ella Hartenian 